Visual Patterns of Dry Blood research report (Vapa & Vapa 2010) shows sample of 158 Finns and their dry blood profiles based on their diets and living habits. The main findings are that vegetarians and those meat eaters who drink purifying liquids (Alkalizers) have the most pure blood. In contrast those who stay up late, are obese (BMI≥30), drink alcohol, smoke or are stressed as well as those who have 4 or more diagnosed diseases (Sickness≥4) have the lowest quality of blood.

Blood purity (Vapa & Vapa 2012) is on average 82% in Finnish population measured from 657 persons. Blood purities below 70% and above 90% are rare. All blood purities below 50% have been measured from hospital patients.

The reliability of blood purity is high. The similarity of two consecutive samples is statistically significant. Pearson correlation is 0,813, p-value < 0,0001 and in average two sample difference is 4,5%. Therefore blood purity is reliable measure of health.

We have also monitored the long-term stability of blood purity with daily and monthly measurements. In the graph shown below the two top-most curves have been measured as one-month period and the other two curves below as measurements with about one-month intervals. The blood purity stays within 5% on daily measurements. Measurements taken each month have higher variety. Patient with aplastic anemia stayed constantly below population average and erythrocyte sedimentation rate was high all the time before death, 46 – 115 mm/h.

As a case example, the figure below shows the diagnosis and treatment process of breast cancer patient. In the beginning of May 2013 the breast cancer diagnosis was ready and before that the low level of blood purity was already seen. The cancer surgery was done at 15.5.2013 and the treatment with cytostatic drugs begun on 27.6.2013 lasting until 11.10.2013. The radiation therapy was given 6.11.2013 – 20.12.2013 almost every day. It can be seen from the graph that the low level of blood purity indicates impaired health.

Master’s thesis work ”Kuivaveren valkoisuus ja kliiniset verimuuttujat” (The whiteness of dry blood and clinical blood variables) in University of Jyväskylä (Kimmo 2014) showed that the whiteness of dry blood correlates with erythrocyte sedimentation rate. Therefore the dry blood method is fast, cheap and easy method to measure inflammation. Model was also developed to estimate dry blood whiteness based on different clinical blood variables. The model is based on the amount of neutrophils, the amount of fibrinogen, the size variation of erythrocytes, the amount of immunoglobulin-A and the amount of hemoglobin. The master’s thesis work also summarizes the history of peer-reviewed dry blood research originating from 1930’s.

The correlations between the whiteness of dry blood samples and clinical blood variables. Spearman correlation is denoted with upper index s. The correlation values higher than 0,300 are bolded. Statistical significance is denoted with a star (p≤0,05 = *, p≤0,01 = ** and p≤0,001 = ***)


Austarheim, K. 1955. Foreign Letters. Journal of the American Medical Association. June 1955. (JAMAForeignLetters686_1955)
Avitabile, G. & Licenziati, M. 1968. Bolen’s test in laryngeal carcinoma and focal tonsillopathy. La Clinica 3: 235 – 241. (pdf)
Bolen H. 1942. The blood pattern as a clue to the diagnosis of malignant disease. The Journal of Laboratory and Clinical Medicine, pp. 1522-1536. (pdf)
Bolen H. 1944. Diagnostic value of blood studies in malignancy of the gastrointestinal tract. The American Journal of Surgery. Volume 63, Issue 3, March 1944, pp. 316–323. (pdf)
Bolen H. 1952. The blood pattern in pre-symptomatic malignancy of the gastrointestinal tract. The American Journal of Digestive Diseases May;19(5):127-30. (pdf)
Brutin, D., Sobac, B., Loquet, B., Sampol, J. 2011. Pattern formation in drying drops of blood, Journal of Fluid Mechanics, Vol. 667, pp. 85-95. (pdf, video)
Goldberger E. 1939. A rapid bedside test for measuring sedimentation rate. New York State Journal of Medicine 39:867. (pdf)
Hawk, B., Thoma, G. & Inkley, J. 1950. An evaluation of the Bolen test as a screening test for malignancy. Cancer Res. 1951 Mar;11(3):157-60. (
Huttunen A. 2013. Kuivaveren puhtauden määrittäminen konenäön avulla. Diplomityö, informaatioverkostojen koulutusohjelma, Oulun yliopisto. (pdf)
Killeen, A., Ossina, N., McGlennen, R., Minnerath, S., Borgos, J., Alexandrov, V., Sarvazyan, A. 2006.Protein Self-Organization Patterns in Dried Serum Reveal Changes in B-cell Disorders. Mol Diagn Ther. 10(6):371-80. (pdf)
Kimmo, A. 2014. Kuivaveren valkoisuus ja kliiniset verimuuttujat, pro gradu -tutkielma, Jyväskylän yliopisto, Liikunta- ja terveystieteellinen tiedekunta, Liikuntabiologian laitos. (pdf)
Nickel, A., Berger, R. & Brickley, P. 1951. The “Bolen Test” in the diagnosis of neoplasms. The American Journal of Digestive Diseases May 1951, Volume 18, Issue 5, pp 150-151 (pdf)
Norman, N. & Slicher, A. 1950. A practical and inexpensive screen test for cancer. Am J Dig Dis. 1950 Feb;17(2):31-7. (pdf)
Pinskaya, I. & Sergeeva, T. 1973. Diagnostic value of the dried blood drop test in cancer. (Bolen’s test) (pdf)
Robertson F. 1944. A Test for Carcinoma. Can Med Assoc J. 1944 July; 51(1): 54–59. (pdf)
Rubik B. 2002. Sympathetic Resonance TechnologyTM: Scientific Foundation and Summary of Biologic and Clinical Studies, The Journal of Alternative and Complementary Medicine, December 2002, 8(6):823-856, (pdf)
Sergel, O., Krylova, N. & Goncharova, Z. 1976. Examination of blood according to Bolen’s method in ambulatory practice. Ter Arkh, 48(8):132-5. (pdf)
Stiller-Winkler, R. & Kuchciński, R. 1966. The Practical Value of the Bolen and Fonti Tests in Oncological Diagnosis. Issues of contemporary oncology. (pdf)
Tarasevich Y. 2004. Mechanisms and models of the dehydration self-organization in biological fluids. Physics – Uspekhi 47 (7) 717 – 728. (pdf)
Vapa M. & Vapa M. 2010. Visual Patterns of Dry Blood as a Possible Health State Indicator. (pdf)
Vapa M. & Vapa M. 2012. Veren puhtaus posteri, Droppi Veripalvelu Oy, Jyväskylän yliopiston liikuntatieteellisen tiedekunnan alumnipäivä 23.11.2012. (pdf)
White, B., Rector, R., Miller, J., Oktavec jr., W. 1952. The Bolen test for cancer. American journal of surgery 84:3 Sep pg 356-7. (pdf)
Yakhno, T., Yakhno, V., Sanin, G., Sanina, O., Pelyushenko, A., Egorove, N., Terentiev, I., Smetanina, S., Korochkina, O., Yashukova, E. 2005. The Informative Capacity Phenomenon of Drying Drops. IEEE Engineering in Medicine and Biology Magazine, Mar-Apr;24(2):96-104. (pdf)